Chronic Fatigue Syndrome (CFS) is a debilitating condition that affects both physical and social aspects of a person’s life. Despite the absence of a universal treatment for CFS, there is hope in the form of Hyperbaric Oxygen Therapy (HBO2). This article delves into a study exploring the potential of HBO2 therapy as a treatment for CFS.

The Challenge of CFS

CFS is a complex, chronic illness characterized by persistent fatigue that disrupts daily life. Finding effective treatments for CFS has been challenging, necessitating innovative approaches.

Hyperbaric Oxygen Therapy (HBO2)

Hyperbaric Oxygen Therapy (HBO2) involves inhaling pure oxygen in a pressurized environment, concentrating the delivery of oxygen to specific areas, similar to the way it aids the healing of wounds. The heightened air pressure in the chamber intensifies the therapeutic effects of oxygen, particularly in areas requiring healing. This concentrated, high-dose oxygen stimulates the mitochondria within cells, enhancing their energy production capabilities. This natural boost in oxygen levels contributes to the therapy’s healing effects, making it a promising avenue for various medical conditions, including Chronic Fatigue Syndrome.

Study Details

Sixteen CFS patients, diagnosed based on Fukuda criteria, underwent fifteen HBO2 therapy sessions over three consecutive weeks (five days per week). The study assessed their condition using various measures, including the Visual Analog Fatigue Scale (VAFS), Fatigue Severity Scale (FSS), and Fatigue Quality of Life Score (FQLS), before and after the treatment.

Positive Outcomes

The study yielded promising results. HBO2 therapy was well-tolerated and significantly improved the patients’ condition. Scores for VAFS, FSS, and FQLS all showed substantial enhancements (all p<0.005).

I have my own personal struggle with chronic fatigue syndrome. I didn’t know diving into our mild hyperbarics would heal my chronic fatigue, or how bad I was actually suffering, but after 15 sessions it was gone permanently. I could finally do laundry and other chores without exhaustion and brain fog. My energy levels tripled and the results were permanent. It may have been from mold exposure, I’m not positive, but I do know I owe my improvements to my soft chamber.

Charlene R


In the challenging landscape of chronic illness, HBO2 therapy offers hope for reducing CFS symptoms and improving patients’ quality of life. While these findings are promising, further research with larger sample sizes and control groups is needed for conclusive validation. Nonetheless, HBO2 therapy shines as a potential avenue for managing the complexities of Chronic Fatigue Syndrome.


Akarsu, S. (2013, March 1). The efficacy of hyperbaric oxygen therapy in the management of chronic fatigue syndrome. National Library of Medicine.